Organic Chemistry

Author: K. Peter C. Vollhardt
Publisher: W. H. Freeman
ISBN: 1464120277
Release Date: 2014-01-01
Genre: Science

With authors who are both accomplished researchers and educators, Vollhardt and Schore's Organic Chemistry takes a functional group approach with a heavy emphasis on understanding how the structure of a molecule determines how that molecule will function in chemical reactions. By understanding the connection between structure and function, students will be better prepared to understand mechanisms and solve practical problems in organic chemistry. The new edition brings in the latest research breakthroughs and applications, expanded problem-solving help, and new online homework options.

Organic Chemistry Palgrave version

Author: K. Peter C. Vollhardt
Publisher: Macmillan International Higher Education
ISBN: 9781319020354
Release Date: 2014-03-11
Genre: Science

With authors who are accomplished researchers and educators, Organic Chemistry helps students understand the connection between structure and function to prepare them to understand mechanisms and solve practical problems in organic chemistry. The new edition brings in the latest research breakthroughs and includes expanded problem-solving help.

Organic Chemistry

Author: K. Peter C. Vollhardt
Publisher: W. H. Freeman
ISBN: 142920494X
Release Date: 2010-01-04
Genre: Science

With authors who are both accomplished researchers and educators, Vollhardt and Schore’s Organic Chemistry is proven effective for making contemporary organic chemistry accessible, introducing cutting-edge research in a fresh, student-friendly way. A wealth of unique study tools help students organize and understand the substantial information presented in this course. And in the sixth edition, the themes of understanding reactivity, mechanisms, and synthetic analysis to apply chemical concepts to realistic situations has been strengthened. New applications of organic chemistry in the life sciences, industrial practices, green chemistry, and environmental monitoring and clean-up are incorporated. This edition includes more than 100 new or substantially revised problems, including new problems on synthesis and green chemistry, and new “challenging” problems.

Organic Chemistry Study Guide with Solutions Manual

Author: Neil E. Schore
Publisher: Macmillan
ISBN: 0716761726
Release Date: 2006-01-04
Genre: Science

The guide includes chapter introductions that highlight new material, chapter outlines, detailed comments for each chapter section, a glossary, and solutions to the end-of-chapter problems, presented in a way that shows students how to reason their way to the answer.

Phthalocyanine Materials

Author: Neil B. McKeown
Publisher: Cambridge University Press
ISBN: 0521496233
Release Date: 1998-07-13
Genre: Science

This monograph describes the preparation, fabrication and structure of phthalocyanine-based materials.

The Organic Chemistry of Drug Design and Drug Action

Author: Richard B. Silverman
Publisher: Academic Press
ISBN: 9780123820310
Release Date: 2014-03-29
Genre: Medical

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. Updates to all chapters, including new examples and references Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry Chapter 3 (Receptors): Drug-receptor interactions, cation-π and halogen bonding; atropisomers; case history of the insomnia drug suvorexant Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates

Dynamics of Proteins and Nucleic Acids

Author: J. Andrew McCammon
Publisher: Cambridge University Press
ISBN: 0521356520
Release Date: 1988-04-29
Genre: Science

This book is a self-contained introduction to the theory of atomic motion in proteins and nucleic acids. An understanding of such motion is essential because it plays a crucially important role in biological activity. The authors, both of whom are well known for their work in this field, describe in detail the major theoretical methods that are likely to be useful in the computer-aided design of drugs, enzymes and other molecules. A variety of theoretical and experimental studies is described and these are critically analyzed to provide a comprehensive picture of dynamic aspects of biomolecular structure and function. The book will be of interest to graduate students and research workers in structural biochemistry (X-ray diffraction and NMR), theoretical chemistry (liquids and polymers), biophysics, enzymology, molecular biology, pharmaceutical chemistry, genetic engineering and biotechnology.

Functional Supramolecular Materials

Author: Rahul Banerjee
Publisher: Royal Society of Chemistry
ISBN: 9781782625407
Release Date: 2017-05-09
Genre: Science

This book provides a comprehensive review of the structure and function of organic and metal-organic supramolecular materials, which will be of interest to students and researchers in this field.

Workbook for Organic Chemistry

Author: Jerry Jenkins
Publisher: Macmillan
ISBN: 9781429247580
Release Date: 2009-12-25
Genre: Science

With authors who are both accomplished researchers and educators, Vollhardt and Schore’s Organic Chemistry is proven effective for making contemporary organic chemistry accessible, introducing cutting-edge research in a fresh, student-friendly way. A wealth of unique study tools help students organize and understand the substantial information presented in this course. And in the sixth edition, the themes of understanding reactivity, mechanisms, and synthetic analysis to apply chemical concepts to realistic situations has been strengthened. New applications of organic chemistry in the life sciences, industrial practices, green chemistry, and environmental monitoring and clean-up are incorporated. This edition includes more than 100 new or substantially revised problems, including new problems on synthesis and green chemistry, and new “challenging” problems.